Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636011 | 0.84 | KMT2A (0.58) | MEN1KMT2ALCKCYP19A1RELA | |
| SCHEMBL15096124 | 0.79 | RELA (0.70) | CYP19A1RELANFE2L2NQO2 | |
| SCHEMBL2723540 | 0.78 | KMT2A (0.68) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28632692 | 0.78 | MEN1 (0.58) | MEN1KMT2ACYP19A1SMN1; SMN2 | |
| SCHEMBL16182836 | 0.75 | RELA (0.50) | MEN1KMT2ALCKCYP19A1RELA | |
| SCHEMBL3821816 | 0.75 | KMT2A (0.68) | MEN1KMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9903153 | 0.74 | KMT2A (0.61) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL13650268 | 0.74 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL16182950 | 0.73 | RELA (0.51) | MEN1KMT2ALCKCYP19A1RELA | |
| SCHEMBL8900000 | 0.72 | KMT2A (0.56) | MEN1KMT2ALCKCYP19A1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |