Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633124 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL29776586 | 0.81 | ALDH1A1 (0.34) | ALDH1A1LMNASLC15A2 | |
| SCHEMBL28356120 | 0.81 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL8155389 | 0.79 | ALDH1A1 (0.77) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL2439884 | 0.79 | ALDH1A1 (0.77) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL11875355 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL15270166 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNASLC15A2KDM4E | |
| SCHEMBL28966701 | 0.76 | ALDH1A1 (0.71) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL7565933 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL18025257 | 0.76 | HTR2C (0.45) | ALDH1A1LMNASLC15A2KDM4EPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387957-B | Spirocyclic indolone-pyrrolidine carbonate compound and composition, preparation method and application thereof | 江苏亚尧生物科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-113387957-A | Spirocyclic indolone-pyrrolidine carbonate compound and composition, preparation method and application thereof | 江苏亚尧生物科技有限公司 | 2021-09-14 | — | — | CN | disclosed |