Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050796 | 0.87 | CSNK2A1 (0.42) | KDM4DCSNK2A1PLATKDM4ENPC1 | |
| SCHEMBL12953361 | 0.86 | KDM4E (0.43) | KDM4DCSNK2A1PLATADORA2AADORA1 | |
| SCHEMBL17085746 | 0.86 | KDM4D (0.42) | KDM4DCSNK2A1PLATKMT2AKDM4E | |
| SCHEMBL15660541 | 0.80 | XDH (0.42) | KDM4DPLAT | |
| SCHEMBL15658303 | 0.80 | ABL1 (0.43) | KDM4DPLATKMT2AKDM4ERXFP1 | |
| SCHEMBL15659374 | 0.79 | KDM4E (0.43) | KDM4DPLATKMT2AKDM4ENPSR1 | |
| SCHEMBL15658307 | 0.77 | CYP2A6 (0.37) | KDM4DCSNK2A1PLATADORA2AADORA1 | |
| SCHEMBL13516175 | 0.76 | PLAT (0.42) | KDM4DPLATKMT2AKDM4ENPC1 | |
| SCHEMBL15661524 | 0.76 | PDE10A (0.42) | PLATADORA1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL17085740 | 0.76 | KDM5A (0.39) | KDM4DCSNK2A1BRD4PLATIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980386-B | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2021-08-13 | — | — | CN | disclosed |