SCHEMBL28633243

SCHEMBL28633243

COc1cc(CCNC(=O)Cc2ccccc2)ccc1O

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
POLB P06746 1/20 0.61
KMT2A Q03164 1/20 0.61
TAAR1 Q96RJ0 1/20 0.61
TRPV1 Q8NER1 1/20 0.60
HSD17B2 P37059 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14703885 0.92 CA1 (0.75) CA1CA2
SCHEMBL6380843 0.90 ALDH1A1 (0.70) CA1CA2POLBKMT2ATAAR1
SCHEMBL2742529 0.88 CA1 (0.82) CA1CA2KMT2A
SCHEMBL21328352 0.88 CA1 (0.78) CA1CA2POLB
SCHEMBL17214300 0.87 CA1 (0.72) CA1CA2
SCHEMBL10604740 0.86 CA1 (0.58) CA1CA2POLBKMT2ATRPV1
SCHEMBL17212236 0.86 CA1 (0.67) CA1CA2
SCHEMBL2925120 0.84 TRPV1 (0.70) CA1CA2POLBKMT2ATRPV1
SCHEMBL9313075 0.84 KMT2A (0.70) CA1CA2POLBKMT2ATAAR1
SCHEMBL28000837 0.84 KMT2A (0.64) POLBKMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113416221-B Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 江西中医药大学 2022-03-11 CN claimed
CN-113416221-A Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 江西中医药大学 2021-09-21 CN claimed
CN-113416221-B Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 江西中医药大学 2022-03-11 CN disclosed
CN-113416221-A Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 江西中医药大学 2021-09-21 CN disclosed