Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151983 | 0.78 | ATR (0.39) | GAAATR | |
| SCHEMBL15237732 | 0.72 | AAK1 (0.38) | AAK1PRMT5WDR77GAAUSP30 | |
| SCHEMBL21318698 | 0.71 | AAK1 (0.46) | AAK1PRMT5WDR77USP30BACE1 | |
| SCHEMBL1255934 | 0.69 | AAK1 (0.54) | AAK1PRMT5WDR77 | |
| SCHEMBL13833256 | 0.68 | AAK1 (0.43) | AAK1PRMT5WDR77USP30BACE1 | |
| SCHEMBL18668117 | 0.68 | KDM4E (0.42) | AAK1PRMT5WDR77 | |
| SCHEMBL20725601 | 0.68 | AAK1 (0.36) | AAK1PRMT5WDR77GAAUSP30 | |
| SCHEMBL20449019 | 0.67 | PRMT5 (0.46) | AAK1PRMT5WDR77USP30BACE1 | |
| SCHEMBL1180976 | 0.67 | AAK1 (0.47) | AAK1PRMT5WDR77USP30BACE1 | |
| SCHEMBL14560 | 0.67 | LIPE (0.48) | AAK1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226322-A | Heterocyclic compounds as BET inhibitors | 诺维逊生物股份有限公司 | 2021-08-06 | — | — | CN | disclosed |