Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658135 | 0.76 | KDM4E (0.41) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL23699545 | 0.75 | KDM4E (0.40) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL5227099 | 0.75 | KDM4E (0.40) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL26087614 | 0.75 | NOTUM (0.46) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL11520043 | 0.73 | KDM4E (0.44) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL5224192 | 0.72 | KDM4E (0.38) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL26091697 | 0.71 | NOTUM (0.46) | NOTUMKDM4EHSD17B10AURKATPX2 | |
| SCHEMBL26089714 | 0.71 | AURKA (0.43) | NOTUMKDM4EHSD17B10MRGPRX4AURKA | |
| SCHEMBL44816 | 0.70 | VCAM1 (0.47) | MEN1KMT2ATDP1HTTALDH1A1 | |
| SCHEMBL14645847 | 0.68 | KDM4E (0.46) | NOTUMKDM4EHSD17B10AURKATPX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423701-A | Substituted isoindolinones | 拜欧斯瑞克斯公司 | 2021-09-21 | — | — | CN | disclosed |