SCHEMBL28633622

SCHEMBL28633622

COC(=O)OCCOCCOC(=O)OCCOCCOC(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
TSHR P16473 5/20 0.41
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
SERPINE1 P05121 1/20 0.33
ABCB11 O95342 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2B P18089 1/20 0.33
OPRD1 P41143 1/20 0.33
SCN5A Q14524 1/20 0.33
ACHE P22303 1/20 0.32
MAPT P10636 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28644452 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL28642740 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL3454202 0.97 ALDH1A1 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL17461587 0.97 ALDH1A1 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL28633091 0.92 ALDH1A1 (0.45) ALDH1A1TSHRHSD17B10SMN1; SMN2ACHE
SCHEMBL20475078 0.91 ALDH1A1 (0.56) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL30179172 0.90 TSHR (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL1128349 0.90 TSHR (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL1469916 0.90 TSHR (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL1471766 0.90 TSHR (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128273-B Synthesis method of di (ethylene glycol methyl carbonate) carbonate 中国科学院成都有机化学有限公司 2021-10-08 CN disclosed