Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27001661 | 0.86 | POLB (0.45) | GSK3BRAB9AMGAMAMY1AGAA | |
| SCHEMBL2336600 | 0.77 | GSK3B (0.51) | GSK3BRAB9AMGAMAMY1AGAA | |
| SCHEMBL28477450 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KMT2AATMHDAC3 | |
| SCHEMBL8772644 | 0.75 | ALDH1A1 (0.50) | RAB9AMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL15287385 | 0.75 | GAA (0.46) | GSK3BRAB9AMGAMAMY1AGAA | |
| SCHEMBL15030280 | 0.75 | ALDH1A1 (0.52) | GSK3BRAB9AMGAMAMY1AGAA | |
| SCHEMBL19964926 | 0.74 | TRIM24 (0.47) | RAB9AGAAMAPTALDH1A1LMNA | |
| SCHEMBL29295631 | 0.74 | ALDH1A1 (0.43) | RAB9AGAAMAPTALDH1A1LMNA | |
| SCHEMBL2330853 | 0.72 | ALDH1A1 (0.53) | GSK3BRAB9AMGAMAMY1AGAA | |
| SCHEMBL28331384 | 0.72 | TRIM24 (0.48) | RAB9AGAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429409-A | Sulfur-containing polysubstituted indolizine compound and preparation method thereof | 浙大城市学院 | 2021-09-24 | — | — | CN | disclosed |