Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206592 | 0.86 | HMGCR (0.48) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL1406216 | 0.80 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL1829725 | 0.76 | CYP4F2 (0.50) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL27941758 | 0.76 | ALDH1A1 (0.32) | PRSS1CTSGCTRB1CMA1ALDH1A1 | |
| SCHEMBL161121 | 0.75 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL779254 | 0.74 | ALDH1A1 (0.38) | CYP2C19HIF1AFFAR3TDP1ALDH1A1 | |
| SCHEMBL28243169 | 0.74 | HMGCR (0.37) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL3851226 | 0.74 | EGLN1 (0.39) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| Propionic Acid SCHEMBL7897446 | 0.73 | FFAR3 (0.62) | CYP2C19HIF1ATSHRFFAR3TDP1 | |
| SCHEMBL7131099 | 0.73 | KDM4E (0.48) | HMGCRCHRM1TBXA2RADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365662-A | Method of treatment | 盖纳万科学有限公司 | 2021-09-07 | — | — | CN | disclosed |