Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550632 | 0.85 | MAPT (0.48) | MAPTPOLBALDH1A1PTGS2BCL9 | |
| SCHEMBL28618738 | 0.80 | HTT (0.50) | MAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL28632633 | 0.80 | MAPT (0.42) | MAPTALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL28614783 | 0.80 | CA12 (0.43) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28615596 | 0.80 | HPGD (0.50) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3581283 | 0.76 | TSHR (0.52) | MAPTPOLBALDH1A1MAPK1CYP2C19 | |
| SCHEMBL1350027 | 0.75 | MAPT (0.57) | MAPTPOLBALDH1A1PTGS2BCL9 | |
| SCHEMBL27819929 | 0.75 | BCL9 (0.58) | MAPTPOLBALDH1A1PTGS2BCL9 | |
| SCHEMBL23732969 | 0.73 | MAPT (0.49) | MAPTALDH1A1BCL9CTNNB1RAB9A | |
| SCHEMBL11142155 | 0.73 | TSHR (0.49) | MAPTPOLBALDH1A1MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307753-B | Preparation method of thioether derivative | 华侨大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-113307753-A | Preparation method of thioether derivative | 华侨大学 | 2021-08-27 | — | — | CN | disclosed |