Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632633 | 0.84 | MAPT (0.42) | KMT2AMEN1CYP1A2L3MBTL1HSD17B10 | |
| SCHEMBL28614783 | 0.84 | CA12 (0.43) | KMT2AMEN1HSD17B10ALDH1A1LMNA | |
| SCHEMBL28618738 | 0.84 | HTT (0.50) | KMT2AL3MBTL1HSD17B10ALDH1A1LMNA | |
| SCHEMBL29182262 | 0.83 | HPGD (0.45) | HPGDKMT2AMEN1CYP1A2ATM | |
| SCHEMBL28507196 | 0.83 | NPC1 (0.37) | HPGDKMT2AMEN1CYP1A2ATM | |
| SCHEMBL28634281 | 0.80 | MAPT (0.52) | KMT2AMEN1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL21946015 | 0.75 | ALDH1A1 (0.48) | KMT2AL3MBTL1HSD17B10ALDH1A1LMNA | |
| SCHEMBL19297529 | 0.74 | ALDH1A1 (0.38) | HPGDKMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7870722 | 0.73 | MMP1 (0.56) | — | |
| SCHEMBL20545052 | 0.73 | CA12 (0.40) | HPGDKMT2AMEN1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307753-B | Preparation method of thioether derivative | 华侨大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-113307753-A | Preparation method of thioether derivative | 华侨大学 | 2021-08-27 | — | — | CN | disclosed |