SCHEMBL28634296

SCHEMBL28634296

Oc1ccc(O)c2cc3ccccc3cc12.Oc1ccc(O)c2cc3ccccc3cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.58
CYP1A2 P05177 3/20 0.55
ALOX5 P09917 2/20 0.50
PTPN22 Q9Y2R2 1/20 0.50
TRPM4 Q8TD43 1/20 0.50
NQO2 P16083 1/20 0.48
POLB P06746 1/20 0.46
HSD17B10 Q99714 2/20 0.44
USP2 O75604 1/20 0.44
PAK1 Q13153 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HDAC3 O15379 1/20 0.44
EP300 Q09472 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT8 Q9H7Z6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392914 1.00 IDO1 (0.58) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL29681720 1.00 IDO1 (0.58) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL28611087 0.95 IDO1 (0.52) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL9353874 0.90 CYP1A2 (0.58) IDO1CYP1A2ALOX5TRPM4NQO2
SCHEMBL11053400 0.86 KMT2A (0.46) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL28118837 0.86 POLB (0.47) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL17846912 0.86 IDO1 (0.61) IDO1CYP1A2ALOX5PTPN22TRPM4
Benzoquinone SCHEMBL28173741 0.86 IDO1 (0.44) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL9621872 0.86 IDO1 (0.44) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL27737884 0.81 CYP1A2 (0.52) CYP1A2ALOX5PTPN22TRPM4NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-214286731-U Distillation plant is used in preparation of blue 35 dyestuff of solvent 安徽清科瑞洁新材料有限公司 2021-09-28 CN disclosed