SCHEMBL392914

SCHEMBL392914

Oc1ccc(O)c2cc3ccccc3cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.58
CYP1A2 P05177 3/20 0.55
ALOX5 P09917 2/20 0.50
PTPN22 Q9Y2R2 1/20 0.50
TRPM4 Q8TD43 1/20 0.50
NQO2 P16083 1/20 0.48
POLB P06746 1/20 0.46
HSD17B10 Q99714 2/20 0.44
USP2 O75604 1/20 0.44
PAK1 Q13153 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HDAC3 O15379 1/20 0.44
EP300 Q09472 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT8 Q9H7Z6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634296 1.00 IDO1 (0.58) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL29681720 1.00 IDO1 (0.58) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL28611087 0.95 IDO1 (0.52) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL9353874 0.90 CYP1A2 (0.58) IDO1CYP1A2ALOX5TRPM4NQO2
SCHEMBL11053400 0.86 KMT2A (0.46) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL28118837 0.86 POLB (0.47) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL17846912 0.86 IDO1 (0.61) IDO1CYP1A2ALOX5PTPN22TRPM4
Benzoquinone SCHEMBL28173741 0.86 IDO1 (0.44) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL9621872 0.86 IDO1 (0.44) IDO1CYP1A2ALOX5PTPN22TRPM4
SCHEMBL27737884 0.81 CYP1A2 (0.52) CYP1A2ALOX5PTPN22TRPM4NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611906-B Tetra (bromoethoxy) anthracene group-containing glycoluril molecular clamp, preparation method and application thereof 西安近代化学研究所 2024-05-10 CN claimed
CN-115611906-A Tetra (bromoethoxy) anthracene-group-containing glycoluril molecular clip, and preparation method and application thereof 西安近代化学研究所 2023-01-17 CN claimed
CN-109734896-B Gemini type stable dispersant, synthesis and application thereof 万华化学集团股份有限公司 2021-06-29 CN claimed
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 EP claimed
CN-108300487-A Liquid crystal display element and polymerizable liquid crystal compound DIC株式会社 2018-07-20 CN claimed
CN-103827126-B Novel compound and carrier for supporting the same 株式会社艾迪科 2017-05-17 CN claimed
US-8900416-B2 Production of higher quality bio-oils by in-line esterification of pyrolysis vapor UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2014-12-02 US claimed
EP-1880429-B1 POLYACENE AND SEMICONDUCTOR FORMULATION MERCK PATENT GMBH (DE) 2012-06-27 EP claimed
US-20110296745-A1 PRODUCTION OF HIGHER QUALITY BIO-OILS BY IN-LINE ESTERIFICATION OF PYROLYSIS VAPOR UNITED STATES DEPARTMENT OF ENERGY 2011-12-08 US claimed
US-7935960-B2 organic field effect transistors; introducing asymmetry into the polyacene derivative affects its solid-state order; combining with organic binder resin results in little or no reduction in charge mobility of the polyacene, even an increase in some instances MERCK PATENT GMBH (DE) 2011-05-03 US claimed
US-20080191199-A1 Polyacene and Semiconductor Formulation FLEXENABLE TECHNOLOGY LIMITED (GB) 2008-08-14 US claimed
US-4323714-A Alkylation of hydroxy-substituted aromatic compounds UOP INC. (US) 1982-04-06 US claimed
JP-61036208-A None JP disclosed
CN-115611906-B Tetra (bromoethoxy) anthracene group-containing glycoluril molecular clamp, preparation method and application thereof 西安近代化学研究所 2024-05-10 CN disclosed
CN-117926361-A Preparation method of imine covalent organic framework film through phenol oxidation 苏州大学 2024-04-26 CN disclosed
WO-2023223923-A1 HYDROXYL GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAYERED PRODUCT DIC株式会社 2023-11-23 WO disclosed
EP-0047781-A1 DYE-FORMING DEVELOPERS. MINNESOTA MINING & MFG (US) 1982-03-24 EP disclosed
WO-1981002797-A1 DYE-FORMING DEVELOPERS MINNESOTA MINING & MFG (US) 1981-10-01 WO disclosed
US-4182918-A Process for the preparation of polyhydric phenols BAYER AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed
US-4051078-A CURING DAINICHI-NIPPON CABLES, LTD. (JA) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080191199-A1 Polyacene and Semiconductor Formulation OR51E2, PIEZO1, FDFT1 IDO1 700/4885CYP1A2 1312/4885ALOX5 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.