Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634359 | 1.00 | GAA (0.40) | GAARAB9ACCR3ABCB1PTPRB | |
| SCHEMBL31232602 | 0.90 | GAA (0.43) | GAARAB9ACCR3ABCB1PTPRB | |
| SCHEMBL22154257 | 0.90 | GAA (0.43) | GAARAB9ACCR3ABCB1PTPRB | |
| SCHEMBL28646537 | 0.87 | GAA (0.37) | GAARAB9ACCR3MAPT | |
| SCHEMBL28631048 | 0.84 | ABCB1 (0.43) | RAB9AABCB1PTPRBMAPT | |
| SCHEMBL28631046 | 0.84 | ABCB1 (0.43) | RAB9AABCB1PTPRBMAPT | |
| SCHEMBL28628655 | 0.83 | RAB9A (0.44) | GAARAB9ACCR3ABCB1PTPRB | |
| SCHEMBL28628657 | 0.83 | RAB9A (0.44) | GAARAB9ACCR3ABCB1PTPRB | |
| SCHEMBL22120966 | 0.83 | GAA (0.44) | GAARAB9ACCR3ABCB1MAOB | |
| SCHEMBL22154261 | 0.83 | ABCB1 (0.41) | RAB9AABCB1PTPRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454097-A | Tubulysins and protein-tubulysin conjugates | 里珍纳龙药品有限公司 | 2021-09-28 | — | — | CN | disclosed |