Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.64 |
| ▸ | PDE4A | P27815 | 7/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120991 | 0.89 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28334312 | 0.89 | PDE4B (0.49) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28333806 | 0.88 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28333752 | 0.86 | APOBEC3G (0.53) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6461060 | 0.82 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29723540 | 0.82 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28628502 | 0.81 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL132715 | 0.80 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL28310127 | 0.79 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL21568180 | 0.79 | PDE4B (0.80) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707873-B | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112707873-A | Substituted oxazole derivative and application thereof in medicine | 广东东阳光药业有限公司 | 2021-04-27 | — | — | CN | disclosed |