Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686256 | 0.86 | TSHR (0.55) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL25224860 | 0.80 | TSHR (0.40) | TSHRSLC1A1KMT2AMEN1CA1 | |
| SCHEMBL3239453 | 0.80 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL4733948 | 0.77 | TSHR (0.44) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL22310262 | 0.76 | TSHR (0.43) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL11592937 | 0.74 | TSHR (0.58) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL23295969 | 0.73 | L3MBTL1 (0.50) | SLC1A1KMT2AKDM4ECA1CA2 | |
| SCHEMBL2821456 | 0.73 | FOLH1 (0.50) | TSHRSLC1A1KDM4ECA1CA2 | |
| SCHEMBL16388417 | 0.73 | TSHR (0.55) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL1406231 | 0.73 | TSHR (0.55) | TSHRSLC1A1KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412260-B | Ketohexokinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-113999212-A | Salts, crystalline forms and uses of ketohexokinase inhibitors | 山东轩竹医药科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113412260-A | Ketohexokinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2021-09-17 | — | — | CN | disclosed |