SCHEMBL28634638

SCHEMBL28634638

CC(=O)Cc1ccc2ccc3cc4ccccc4c4ccc1c2c34

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.56
ERBB2 P04626 1/20 0.56
FYN P06241 1/20 0.56
MAOA P21397 1/20 0.56
ACHE P22303 1/20 0.56
AHR P35869 1/20 0.56
ALDH1A1 P00352 5/20 0.46
HPGD P15428 4/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HSD17B10 Q99714 2/20 0.39
THRB P10828 1/20 0.39
AKR1B1 P15121 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP2C19 P33261 2/20 0.38
GLA P06280 1/20 0.38
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046939 0.84 KMT2A (0.57) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL28634641 0.81 CYP1A2 (0.79) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28668047 0.77 KMT2A (0.74) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL11390112 0.77 CYP1A2 (0.61) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28630441 0.76 TDP1 (0.56) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL6264675 0.75 CYP1A2 (0.87) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1288207 0.75 CYP1A2 (0.86) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL30122951 0.75 CYP1A2 (0.86) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1096241 0.75 CYP1A2 (0.86) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29746490 0.75 CYP1A2 (0.86) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333942-A Method for promoting bacteria to degrade benzo [ a ] pyrene by using biostimulant and application of method 华南理工大学 2023-06-27 CN disclosed
CN-114107116-A Rhodococcus with function of degrading benzo [ a ] pyrene 北京师范大学 2022-03-01 CN disclosed
CN-113462590-A Preparation of compound microbial agent and application of compound microbial agent in degradation of pollutant polycyclic aromatic hydrocarbon 中国矿业大学 2021-10-01 CN disclosed