Benzo[Def]Chrysene

Benzo[Def]Chrysene

SCHEMBL28634641

CC(C)=O.c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.79
FYN P06241 2/20 0.79
ACHE P22303 2/20 0.79
AHR P35869 2/20 0.79
ERBB2 P04626 1/20 0.79
MAOA P21397 1/20 0.79
ALDH1A1 P00352 10/20 0.54
HPGD P15428 8/20 0.54
MAPT P10636 3/20 0.54
HSD17B10 Q99714 7/20 0.52
THRB P10828 1/20 0.52
KDM4E B2RXH2 3/20 0.51
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
TSHR P16473 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CYP3A4 P08684 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GLA P06280 2/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[Def]Chrysene SCHEMBL29352452 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL29826740 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL30358490 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL24019 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL29407951 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL23414475 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL17114373 0.89 CYP1A2 (1.00) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL2726094 0.87 CYP1A2 (0.88) CYP1A2FYNACHEAHRERBB2
SCHEMBL4852478 0.87 CYP1A2 (0.96) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL11393448 0.87 CYP1A2 (0.96) CYP1A2FYNACHEAHRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333942-A Method for promoting bacteria to degrade benzo [ a ] pyrene by using biostimulant and application of method 华南理工大学 2023-06-27 CN disclosed
CN-114107116-A Rhodococcus with function of degrading benzo [ a ] pyrene 北京师范大学 2022-03-01 CN disclosed
CN-113462590-A Preparation of compound microbial agent and application of compound microbial agent in degradation of pollutant polycyclic aromatic hydrocarbon 中国矿业大学 2021-10-01 CN disclosed