Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198267 | 0.82 | KDM4E (0.45) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL29065142 | 0.81 | MAPT (0.67) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL29365596 | 0.78 | MEN1 (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL15691572 | 0.78 | MEN1 (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL900116 | 0.78 | MEN1 (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL45826 | 0.78 | MEN1 (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL14848413 | 0.77 | MEN1 (0.50) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL6756888 | 0.75 | MEN1 (0.59) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| Phenol SCHEMBL8103114 | 0.75 | MEN1 (0.59) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL13973848 | 0.75 | MEN1 (0.49) | MEN1KMT2ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | claimed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | claimed |
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | disclosed |