Phenol

Phenol

SCHEMBL8103114

Oc1ccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)cc1.Oc1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
LMNA P02545 3/20 0.59
MAPT P10636 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
KDM4E B2RXH2 1/20 0.59
OPRK1 P41145 1/20 0.59
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
TDP1 Q9NUW8 3/20 0.49
GPR55 Q9Y2T6 3/20 0.49
CHRM2 P08172 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
KCNH2 Q12809 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TP53 P04637 1/20 0.49
TYMS P04818 1/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756888 0.96 MEN1 (0.59) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL45826 0.96 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL15691572 0.96 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL29365596 0.96 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL900116 0.96 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
Bicarbonate SCHEMBL4853074 0.92 MEN1 (0.55) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL18184916 0.90 MMP3 (0.56) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL25230386 0.90 MEN1 (0.57) MEN1KMT2ALMNAMAPTSMN1; SMN2
Formaldehyde SCHEMBL972884 0.90 MEN1 (0.57) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL12938480 0.90 MEN1 (0.57) MEN1KMT2ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5463140-A Condensing aldehyde or ketone with phenol in presence of soluble or insoluble mercaptosulfonic acid compound to form geminal bisphenol moiety at each aldehyde or ketone moiety THE DOW CHEMICAL COMPANY (US) 1995-10-31 US claimed
US-6133190-A SUPPORTED MERCAPTOAKYL-SUBSTITUTED POLYSTYRENESULFONATE IS USED AS A CATALYST FOR CONDENSATION OF ALDEHYDE OR KETONE WITH PHENOL TO FORM DIHYDROXY COMPOUND THE DOW CHEMICAL COMPANY (US) 2000-10-17 US disclosed
US-6051658-A A POLYSTYRENE HAVING MERCAPTOSULFONIC ACID RESIDUE, USEFUL AS CATALYST THE DOW CHEMICAL COMPANY (US) 2000-04-18 US disclosed
US-5939494-A CATALYST USEFUL FOR THE CONDENSATION OF AN ALDEHYDE OR KETONE STARTING MATERIAL WITH A PHENOL IS AN INSOLUBLE MERCAPTOSULFONIC ACID COMPOUND THE DOW CHEMICAL COMPANY (US) 1999-08-17 US disclosed
EP-0848693-A4 ISOMERIZATION OF BISPHENOLS DOW CHEMICAL CO (US) 1999-03-17 EP disclosed
EP-0848693-A1 ISOMERIZATION OF BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1998-06-24 EP disclosed
WO-1997008122-A1 ISOMERIZATION OF BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1997-03-06 WO disclosed
US-5463140-A Condensing aldehyde or ketone with phenol in presence of soluble or insoluble mercaptosulfonic acid compound to form geminal bisphenol moiety at each aldehyde or ketone moiety THE DOW CHEMICAL COMPANY (US) 1995-10-31 US disclosed