SCHEMBL2863515

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867399	0.89	EGFR (0.50)	NTRK1MAP2K4EGFRMAPK1HDAC1
	SCHEMBL13198260	0.83	NTRK1 (0.49)	NTRK1MAP2K4EGFRMAPK1GSK3B
	SCHEMBL2855841	0.83	TTK (0.52)	NTRK1MAP2K4POLB
	SCHEMBL4335912	0.83	CDK9 (0.49)	NTRK1MAP2K4MAPK1CLK2CLK3
	SCHEMBL13198259	0.82	GSK3B (0.60)	NTRK1MAP2K4HDAC1HDAC2HDAC8
	SCHEMBL13198285	0.81	KDM4E (0.51)	MAPK1POLB
	SCHEMBL2858421	0.78	MAP2K4 (0.58)	NTRK1MAP2K4
	SCHEMBL13198283	0.77	GSK3A (0.45)	NTRK1MAP2K4EGFRMAPK1GSK3B
	SCHEMBL4326338	0.77	GSK3A (0.45)	NTRK1MAP2K4EGFRMAPK1GSK3B
	SCHEMBL2867504	0.77	CDK4 (0.45)	MAPK1HDAC1HDAC2HDAC8GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.