Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.45 |
| ▸ | MGLL | Q99685 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23983021 | 1.00 | PTGS1 (0.45) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| Trifluoroacetic Acid SCHEMBL23113666 | 0.93 | SLC15A2 (0.40) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| Trifluoroacetic Acid SCHEMBL23113668 | 0.93 | SLC15A2 (0.40) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| SCHEMBL28624192 | 0.87 | GNPAT (0.52) | MGLLFAAHSLC15A2GNPATGSK3A | |
| SCHEMBL28624188 | 0.87 | GNPAT (0.52) | MGLLFAAHSLC15A2GNPATGSK3A | |
| SCHEMBL31722260 | 0.86 | SLC6A5 (0.54) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| SCHEMBL31722125 | 0.86 | SLC6A5 (0.54) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| SCHEMBL21152612 | 0.86 | SLC6A5 (0.54) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| SCHEMBL29695436 | 0.86 | SLC6A5 (0.54) | PTGS1PTGS2MGLLFAAHSLC15A2 | |
| SCHEMBL12914891 | 0.86 | SLC6A5 (0.54) | PTGS1PTGS2MGLLFAAHSLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |
| CN-112135841-A | Complexes comprising anti-human MUC1 antibody Fab fragments, peptide linkers, and/or ligands | 安斯泰来制药株式会社 | 2020-12-25 | — | — | CN | disclosed |