Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30897306 | 1.00 | TSPO (0.82) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL410057 | 0.91 | TSPO (1.00) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL410188 | 0.91 | TSPO (1.00) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL409626 | 0.91 | TSPO (1.00) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL18806386 | 0.91 | TSPO (1.00) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL10287450 | 0.91 | TSPO (1.00) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL30897308 | 0.89 | TSPO (0.64) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL28641677 | 0.89 | TSPO (0.64) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL30897310 | 0.83 | TSPO (0.83) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL28629825 | 0.83 | TSPO (0.83) | TSPOCYP1A2CYP2C19OPRM1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402444-A | Carbazole compound and application thereof in preparation of medicines for treating metabolic related diseases such as fatty liver and type 2 diabetes | 上海欧坤生物医药科技有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-113402444-B | Carbazole compound and application thereof in preparation of medicines for treating fatty liver and type 2 diabetes and other metabolic related diseases | 上海欧坤生物医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113402444-A | Carbazole compound and application thereof in preparation of medicines for treating metabolic related diseases such as fatty liver and type 2 diabetes | 上海欧坤生物医药科技有限公司 | 2021-09-17 | — | — | CN | disclosed |