SCHEMBL2863568

SCHEMBL2863568

CCCCCOc1cc2c3cc(OCCCCC)c(OCCCCC)cc3c3cc(OCCCCCCCCCCCCCCCCCC[Si](Cl)(Cl)Cl)c(OCCCCC)cc3c2cc1OCCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 2/20 0.40
▸ EGFR P00533 1/20 0.38
▸ SMPD1 P17405 5/20 0.38
▸ ENPP1 P22413 1/20 0.37
▸ MCHR1 Q99705 1/20 0.37
▸ SRC P12931 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ NR1I2 O75469 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ CHRM2 P08172 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ ADRA2A P08913 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ OPRK1 P41145 1/20 0.36
▸ HTR2B P41595 1/20 0.36
▸ SLC6A3 Q01959 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ HDAC6 Q9UBN7 1/20 0.36
▸ CHUK O15111 1/20 0.36
▸ DAPK3 O43293 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852415 0.97 PDE3B (0.38) TLR8EGFRSMPD1ENPP1MCHR1
SCHEMBL2859962 0.86 CNR2 (0.39) TLR8EGFRMEN1LMNAMAPT
SCHEMBL12918761 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL20678395 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL31071684 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL8975367 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL8974623 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL8974064 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL202536 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA
SCHEMBL6743869 0.85 NR5A1 (0.45) TLR8SMPD1MEN1NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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