SCHEMBL2859962

SCHEMBL2859962

CCCCCOc1cc2c3cc(OCCCCC)c(OCCCCC)cc3c3cc(SCCCCCCCCCCCCCCCCCC[Si](Cl)(Cl)Cl)c(OCCCCC)cc3c2cc1OCCCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.39
▸ PTGS2 P35354 3/20 0.35
▸ LMNA P02545 3/20 0.33
▸ HTT P42858 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ GPR84 Q9NQS5 6/20 0.33
▸ TLR8 Q9NR97 1/20 0.33
▸ EGFR P00533 1/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ NSD2 O96028 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860389 0.97 CNR2 (0.39) CNR2PTGS2LMNAHTTNPC1
SCHEMBL2859062 0.96 LMNA (0.36) CNR2PTGS2LMNAHTTNPC1
SCHEMBL2861736 0.94 CNR2 (0.35) CNR2PTGS2LMNAHTTNPC1
SCHEMBL2860136 0.87 CNR2 (0.39) CNR2PTGS2LMNAHTTNPC1
SCHEMBL9011674 0.86 CNR2 (0.43) CNR2PTGS2LMNAHTTNPC1
SCHEMBL2863568 0.86 TLR8 (0.40) LMNATLR8EGFRMAPTMEN1
SCHEMBL2863459 0.86 CNR2 (0.38) CNR2PTGS2LMNAHTTNPSR1
SCHEMBL2859051 0.85 GPR84 (0.39) PTGS2LMNAUSP2HSD17B10GPR84
SCHEMBL2852351 0.85 CNR2 (0.39) CNR2PTGS2LMNAHTTNPC1
SCHEMBL2866418 0.84 CNR2 (0.38) CNR2PTGS2LMNAHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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