Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.38 |
| ▸ | NNMT | P40261 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626751 | 0.90 | METTL3 (0.50) | METTL3PRMT5WDR77 | |
| SCHEMBL20049699 | 0.84 | METTL3 (0.41) | METTL3PRMT5WDR77NNMT | |
| SCHEMBL18571897 | 0.84 | PRMT5 (0.46) | METTL3PRMT5WDR77NNMT | |
| SCHEMBL18572838 | 0.83 | PRMT5 (0.58) | METTL3PRMT5WDR77NNMT | |
| SCHEMBL18572002 | 0.83 | METTL3 (0.52) | METTL3PRMT5WDR77 | |
| SCHEMBL23892543 | 0.82 | PRMT5 (0.46) | METTL3PRMT5WDR77NNMT | |
| SCHEMBL18571999 | 0.82 | PRMT5 (0.46) | METTL3PRMT5WDR77NNMT | |
| SCHEMBL20049615 | 0.81 | PRMT5 (0.38) | METTL3PRMT5WDR77NNMT | |
| SCHEMBL22002070 | 0.81 | PRMT5 (0.62) | METTL3PRMT5WDR77 | |
| SCHEMBL28922193 | 0.80 | METTL3 (0.36) | METTL3PRMT5WDR77NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234079-B | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113234079-A | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2021-08-10 | — | — | CN | disclosed |