Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636204 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2FAPCTSKABCB1KDM4E | |
| SCHEMBL22154601 | 0.99 | FAP (0.36) | SMN1; SMN2FAPCTSKABCB1KDM4E | |
| SCHEMBL28628684 | 0.93 | FAP (0.36) | FAP | |
| SCHEMBL22154266 | 0.93 | FAP (0.36) | FAP | |
| SCHEMBL28628682 | 0.93 | FAP (0.36) | FAP | |
| SCHEMBL22154614 | 0.92 | SMN1; SMN2 (0.36) | SMN1; SMN2FAPCTSKABCB1KDM4E | |
| SCHEMBL28633861 | 0.92 | SMN1; SMN2 (0.36) | SMN1; SMN2FAPCTSKABCB1KDM4E | |
| SCHEMBL22154590 | 0.92 | FAP (0.37) | FAP | |
| SCHEMBL28634362 | 0.92 | FAP (0.37) | FAP | |
| SCHEMBL28634363 | 0.92 | FAP (0.37) | FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454097-A | Tubulysins and protein-tubulysin conjugates | 里珍纳龙药品有限公司 | 2021-09-28 | — | — | CN | disclosed |