Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049910 | 0.89 | KLKB1 (0.40) | L3MBTL1KLKB1FFAR1ITKLIPG | |
| SCHEMBL21089705 | 0.82 | SCD (0.40) | KLKB1FFAR1ITKALDH1A1HDAC1 | |
| SCHEMBL21089816 | 0.72 | FFAR1 (0.52) | L3MBTL1KLKB1FFAR1LIPGMEN1 | |
| SCHEMBL98814 | 0.72 | FFAR1 (0.56) | L3MBTL1KLKB1FFAR1LIPGSCD | |
| SCHEMBL14858425 | 0.71 | LIPG (0.50) | L3MBTL1KLKB1FFAR1LIPGMEN1 | |
| SCHEMBL22777159 | 0.71 | FFAR1 (0.47) | KLKB1FFAR1LIPGF2F11 | |
| SCHEMBL14165519 | 0.70 | FFAR1 (0.47) | L3MBTL1KLKB1FFAR1LIPGMEN1 | |
| SCHEMBL13736818 | 0.70 | KLKB1 (0.46) | L3MBTL1KLKB1FFAR1LIPGALDH1A1 | |
| SCHEMBL13737711 | 0.70 | CD74 (0.49) | L3MBTL1KLKB1FFAR1POLBTDP1 | |
| SCHEMBL29736831 | 0.70 | CD74 (0.49) | L3MBTL1KLKB1FFAR1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689661-B | Macrocyclic inhibitors of myeloperoxidase | 百时美施贵宝公司 | 2021-10-15 | — | — | CN | disclosed |