Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863649 | 1.00 | P2RX3 (0.65) | P2RX3P2RX2 | |
| SCHEMBL2857793 | 0.93 | P2RX3 (0.66) | P2RX3P2RX2 | |
| SCHEMBL2857791 | 0.93 | P2RX3 (0.66) | P2RX3P2RX2 | |
| SCHEMBL2865768 | 0.84 | P2RX3 (0.73) | P2RX3P2RX2 | |
| SCHEMBL4759612 | 0.83 | P2RX3 (0.75) | P2RX3P2RX2 | |
| SCHEMBL4759616 | 0.83 | P2RX3 (0.75) | P2RX3P2RX2 | |
| SCHEMBL2862055 | 0.80 | P2RX3 (0.73) | P2RX3P2RX2 | |
| SCHEMBL2862875 | 0.80 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL2879101 | 0.79 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL15063107 | 0.79 | P2RX3 (1.00) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139334-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008130481-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |