Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644992 | 0.89 | KDM1A (0.45) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28859038 | 0.87 | BTK (0.59) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL29989719 | 0.86 | BTK (0.46) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28645870 | 0.86 | BTK (0.46) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28925175 | 0.80 | KDM1A (0.43) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28647880 | 0.78 | EGFR (0.45) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28636598 | 0.76 | BTK (0.54) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28643794 | 0.74 | BTK (0.44) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL29989351 | 0.74 | BTK (0.48) | BTKEGFRERBB2BLKBMX | |
| SCHEMBL28657063 | 0.72 | ERBB2 (0.43) | BTKEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493439-B | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113493439-A | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-10-12 | — | — | CN | disclosed |