Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581875 | 0.98 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2ALDH1A1LMNAUSP2 | |
| SCHEMBL7487765 | 0.94 | CYP2C19 (0.48) | CYP2C19SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL12314309 | 0.84 | CYP2C19 (0.39) | CYP2C19SMN1; SMN2LMNAOPRM1POLB | |
| SCHEMBL28043400 | 0.84 | CYP2C19 (0.37) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL1142569 | 0.82 | SMN1; SMN2 (0.39) | CYP2C19SMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL12265852 | 0.82 | LMNA (0.41) | CYP2C19SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL12265851 | 0.82 | CYP2C19 (0.37) | CYP2C19SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2185965 | 0.81 | CYP4F2 (0.40) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL13904685 | 0.81 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2ALDH1A1LMNAUSP2 | |
| SCHEMBL12999536 | 0.81 | CYP2C19 (0.47) | CYP2C19SMN1; SMN2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113391020-A | Thin-layer identification method for sinopodophyllum hexandrum | 中国科学院西北高原生物研究所 | 2021-09-14 | — | — | CN | disclosed |