Chloroform

Chloroform

SCHEMBL28636650

ClC(Cl)Cl.Nc1c(Br)cc(Br)cc1C=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.50
PTPN1 P18031 1/20 0.37
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
GSK3B P49841 1/20 0.32
PRKDC P78527 1/20 0.32
CA3 P07451 1/20 0.32
ABCB11 O95342 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
AR P10275 1/20 0.30
CYP2D6 P10635 1/20 0.30
SLC6A2 P23975 1/20 0.30
PDE4A P27815 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KCNH2 Q12809 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27987006 0.92 ERN1 (0.57) ERN1PTPN1GAAMAPTCA1
SCHEMBL285148 0.92 ERN1 (0.57) ERN1PTPN1GAAMAPTCA1
SCHEMBL29353535 0.92 ERN1 (0.57) ERN1PTPN1GAAMAPTCA1
SCHEMBL16668856 0.76 ERN1 (0.44) ERN1PTPN1MAPTCA1CA2
SCHEMBL2428055 0.76 ERN1 (0.60) ERN1PTPN1GAAMAPTCA1
SCHEMBL23301104 0.72 ERN1 (0.44) ERN1GAAMAPTCA1CA2
SCHEMBL1571069 0.72 ERN1 (0.44) ERN1GAAMAPTCA1CA2
SCHEMBL5649939 0.72 ERN1 (0.48) ERN1GAAMAPTCA1CA2
SCHEMBL13368512 0.72 ERN1 (0.44) ERN1PTPN1CA1CA2CA9
SCHEMBL2312545 0.72 ERN1 (0.44) ERN1PTPN1PRKDCCYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444004-B 3, 5-dibromo-o-amino benzaldehyde production process 江西荣兴药业有限公司 2023-06-23 CN claimed
CN-113444004-A Production process of 3, 5-dibromo anthranilic aldehyde 江西荣兴药业有限公司 2021-09-28 CN claimed
CN-113444004-B 3, 5-dibromo-o-amino benzaldehyde production process 江西荣兴药业有限公司 2023-06-23 CN disclosed
CN-113444004-A Production process of 3, 5-dibromo anthranilic aldehyde 江西荣兴药业有限公司 2021-09-28 CN disclosed