Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987006 | 1.00 | ERN1 (0.57) | ERN1PTPN1GAAMAPTCA1 | |
| SCHEMBL29353535 | 1.00 | ERN1 (0.57) | ERN1PTPN1GAAMAPTCA1 | |
| Chloroform SCHEMBL28636650 | 0.92 | ERN1 (0.50) | ERN1PTPN1GAAMAPTCA1 | |
| SCHEMBL1571069 | 0.78 | ERN1 (0.44) | ERN1GAAMAPTCA1CA2 | |
| SCHEMBL13368512 | 0.78 | ERN1 (0.44) | ERN1PTPN1CA1CA2CA9 | |
| SCHEMBL23301104 | 0.78 | ERN1 (0.44) | ERN1GAAMAPTCA1CA2 | |
| SCHEMBL16668856 | 0.78 | ERN1 (0.44) | ERN1PTPN1MAPTCA1CA2 | |
| SCHEMBL2428055 | 0.78 | ERN1 (0.60) | ERN1PTPN1GAAMAPTCA1 | |
| SCHEMBL5649939 | 0.78 | ERN1 (0.48) | ERN1GAAMAPTCA1CA2 | |
| SCHEMBL2312545 | 0.78 | ERN1 (0.44) | ERN1PTPN1PRKDCCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001260-B1 | DIBROMOBENZYL DERIVATIVE, STEREOISOMER OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHENGDU SHIBEIKANG BIOMEDICAL TECH CO LTD (CN) | 2025-10-08 | — | — | EP | claimed |
| CN-120117949-A | Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine | 湖南大学 | 2025-06-10 | — | — | CN | claimed |
| CN-118125928-B | Preparation method of 2-amino-3, 5-dibromobenzaldehyde | 南昌大学抚州医学院 | 2025-03-28 | — | — | CN | claimed |
| CN-119504447-A | Preparation method of bromhexine hydrochloride | 浙江海洲制药股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119192442-A | Material for hydrophilic modification of polytetrafluoroethylene microporous membrane and preparation method thereof | 浙江东大环境工程有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118976383-A | Polytetrafluoroethylene microporous membrane, hydrophilic modification method thereof and water treatment device | 浙江东大环境工程有限公司 | 2024-11-19 | — | — | CN | claimed |
| US-12006276-B2 | Dibromobenzyl derivative, stereoisomer or salt thereof, and preparation method and application of dibromobenzyl derivative | CHENGDU SHIBEIKANG BIOMEDICAL TECHNOLOGY CO., LTD. (CN) | 2024-06-11 | — | — | US | claimed |
| CN-118125928-A | Preparation method of 2-amino-3, 5-dibromobenzaldehyde | 南昌大学抚州医学院 | 2024-06-04 | — | — | CN | claimed |
| CN-118047681-A | Preparation method of bromhexine hydrochloride | 仁合益康集团有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117903212-A | Iridium complex and application thereof in preparation of antitumor drugs | 华南农业大学 | 2024-04-19 | — | — | CN | claimed |
| CN-104003887-A | Preparation method of bromhexine hydrochloride | YU ZHONGHUA | 2014-08-27 | — | — | CN | claimed |
| CN-102153482-B | Method for refining injection-level ambroxol hydrochloride, product and injection thereof | TIANJIN MINGTAI MEDICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-103012167-A | Preparation method of ambroxol hydrochloride | CSPC ZHONGNUO PHARMACEUTICAL SHIJIAZHUANG CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-102153482-A | Method for refining injection-level ambroxol hydrochloride, product and injection thereof | TIANJIN MINGTAI MEDICAL TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | claimed |
| CN-101865891-A | Ambroxol hydrochloride detection method | YUNNAN LONGHAI NATURAL PLANT MEDICINE INDUSTRY CO LTD | 2010-10-20 | — | — | CN | claimed |
| US-6797745-B1 | Hot melt inks containing styrene or terpene polymers | XEROX CORPORATION | 2004-09-28 | — | — | US | claimed |
| US-6780900-B1 | ALDEHYDE COPOLYMER INK VEHICLE, A NONPOLYMERIC ALDEHYDE VISCOSITY MODIFIER, COLORANT, AN OPTIONAL CONDUCTIVITY ENHANCING AGENT, AN OPTIONAL ANTIOXIDANT, AND AN OPTIONAL UV ABSORBER | XEROX CORPORATION | 2004-08-24 | — | — | US | claimed |
| EP-0147475-B1 | AMINOCYCLOHEXANOL DERIVATIVES HAVING AN EXPECTORANT ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MAGIS FARMACEUTICI S.p.A. (IT) | 1987-03-18 | — | — | EP | claimed |
| EP-0147475-A1 | Aminocyclohexanol derivatives having an expectorant activity, process for their preparation and pharmaceutical compositions containing them | MAGIS FARMACEUTICI S.p.A. (IT) | 1985-07-10 | — | — | EP | claimed |
| US-4528393-A | Derivatives having expectorant activity, the procedure for their preparation and the pharmaceutical compositions which contain them | MAGIS FARMACEUTICI S.R.L. (IT) | 1985-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12006276-B2 | Dibromobenzyl derivative, stereoisomer or salt thereof, and preparation method and application of dibromobenzyl derivative | CYP11B2, CYP11B1, CYP46A1 | ERN1 2948/4885PTPN1 1942/4885GAA 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.