Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL15412712 | 0.91 | FFAR3 (0.39) | FFAR3 | |
| SCHEMBL25266 | 0.84 | — | — | |
| Alcohol SCHEMBL28228159 | 0.82 | ADRA2A (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL27742777 | 0.82 | ADRA2A (0.32) | — | |
| SCHEMBL3919995 | 0.82 | ADRA2A (0.32) | — | |
| Propane SCHEMBL28148423 | 0.82 | ADRA2A (0.32) | — | |
| SCHEMBL6683456 | 0.82 | — | — | |
| Acetic Acid SCHEMBL4074356 | 0.81 | GAA (0.33) | — | |
| SCHEMBL10755796 | 0.81 | — | — | |
| Oxirane SCHEMBL28312924 | 0.80 | ADRA2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113384530-A | Polysaccharide core Nanocells and preparation method and application thereof | 暨南大学 | 2021-09-14 | — | — | CN | claimed |
| CN-113384530-B | Polysaccharide core Nanocells and preparation method and application thereof | 暨南大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113384530-A | Polysaccharide core Nanocells and preparation method and application thereof | 暨南大学 | 2021-09-14 | — | — | CN | disclosed |