Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.76 |
| ▸ | TP53 | P04637 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.75 |
| ▸ | USP2 | O75604 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696195 | 0.93 | MAPT (0.69) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28696162 | 0.92 | TP53 (0.78) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28686549 | 0.91 | TP53 (0.69) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28705219 | 0.90 | MAPT (0.66) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28690133 | 0.89 | TP53 (0.67) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL14984406 | 0.89 | MEN1 (0.70) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28690164 | 0.88 | TP53 (0.66) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28932884 | 0.86 | ALDH1A1 (1.00) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28690093 | 0.85 | TP53 (0.62) | MAPTTP53ALDH1A1USP2HSD17B10 | |
| SCHEMBL28705958 | 0.82 | MAPT (0.76) | MAPTTP53ALDH1A1USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113456631-B | Small molecule drug targeting ACSL1 and application thereof in treatment of endometrial cancer | 徐州医科大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-113456631-A | Small molecule drug targeting ACSL1 and application thereof in treatment of endometrial cancer | 徐州医科大学 | 2021-10-01 | — | — | CN | disclosed |