Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.39 |
| ▸ | JAK1 | P23458 | 6/20 | 0.38 |
| ▸ | JAK3 | P52333 | 6/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397011 | 0.85 | L3MBTL1 (0.50) | L3MBTL1IKBKETBK1JAK1JAK3 | |
| SCHEMBL2828291 | 0.85 | L3MBTL1 (0.68) | L3MBTL1IKBKETBK1JAK1JAK3 | |
| SCHEMBL22183009 | 0.84 | L3MBTL1 (0.49) | L3MBTL1IKBKETBK1JAK1JAK3 | |
| SCHEMBL22064000 | 0.84 | L3MBTL1 (0.49) | L3MBTL1IKBKETBK1JAK1JAK3 | |
| SCHEMBL18397398 | 0.81 | L3MBTL1 (0.46) | L3MBTL1IKBKETBK1JAK1JAK3 | |
| SCHEMBL2823114 | 0.80 | L3MBTL1 (0.49) | L3MBTL1HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL3063805 | 0.78 | L3MBTL1 (0.51) | L3MBTL1ACHEHPGDLMNAKDM4E | |
| SCHEMBL2828436 | 0.76 | L3MBTL1 (0.44) | L3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL23535650 | 0.75 | L3MBTL1 (0.50) | L3MBTL1IKBKETBK1PRKAA1PRKAB2 | |
| SCHEMBL1663037 | 0.74 | MEN1 (0.45) | L3MBTL1IKBKETBK1JAK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227070-A | ASK1 inhibitors | 比奥根MA公司 | 2021-08-06 | — | — | CN | disclosed |