Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385739 | 1.00 | LMNA (0.44) | LMNAKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL1385740 | 1.00 | LMNA (0.44) | LMNAKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL345484 | 0.79 | SMN1; SMN2 (0.40) | LMNAKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL343573 | 0.79 | SMN1; SMN2 (0.40) | LMNAKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL26724613 | 0.79 | SMN1; SMN2 (0.40) | LMNAKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL27572840 | 0.78 | GLA (0.56) | LMNAKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL1344065 | 0.77 | — | — | |
| SCHEMBL10022729 | 0.77 | — | — | |
| SCHEMBL4399382 | 0.77 | — | — | |
| SCHEMBL12552290 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527307-B | Triazolyl-containing benzocyclic derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113549074-A | Triazole group-containing fused ring derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113527307-A | Triazole group-containing fused ring derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-22 | — | — | CN | disclosed |