SCHEMBL28637109

SCHEMBL28637109

Oc1ccc(C(CCc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
KCNH2 Q12809 3/20 0.54
ADRA1A P35348 2/20 0.54
OPRK1 P41145 2/20 0.54
LMNA P02545 1/20 0.54
ADRB2 P07550 1/20 0.54
ADRB1 P08588 1/20 0.54
HTR1A P08908 1/20 0.54
ADRA2A P08913 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
SLC6A2 P23975 1/20 0.54
HTR2A P28223 1/20 0.54
OPRM1 P35372 1/20 0.54
DRD3 P35462 1/20 0.54
HTR2B P41595 1/20 0.54
SLC6A3 Q01959 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9650195 0.98 MEN1 (0.57) MEN1KMT2AKCNH2ADRA1AOPRK1
SCHEMBL3120648 0.96 MEN1 (0.64) MEN1KMT2AKCNH2ADRA1AOPRK1
SCHEMBL985018 0.94 MEN1 (0.66) MEN1KMT2AKCNH2ADRA1AOPRK1
SCHEMBL611095 0.90 ESR1 (0.56) MEN1KMT2AKCNH2ADRA1AOPRK1
SCHEMBL6497060 0.87 KCNH2 (0.63) MEN1KMT2AKCNH2ADRA1AOPRK1
SCHEMBL9652888 0.86 KCNH2 (0.51) MEN1KMT2AKCNH2ADRA1AOPRK1
SCHEMBL5604561 0.85 MEN1 (0.56) MEN1KMT2AKCNH2HTR2ACNR1
SCHEMBL10882091 0.83 MEN1 (0.55) MEN1KMT2AKCNH2LMNAADRA2A
SCHEMBL5604688 0.83 MEN1 (0.55) MEN1KMT2AKCNH2LMNAADRA2A
SCHEMBL9460360 0.82 ADRA1A (0.56) KCNH2ADRA1AOPRK1LMNAADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109804310-B Negative photosensitive resin composition, cured film, element and display device provided with cured film, and method for producing same 东丽株式会社 2022-09-30 CN disclosed
CN-114460809-A Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-05-10 CN disclosed
CN-108885399-B Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-03-15 CN disclosed
CN-108027561-B Negative photosensitive resin composition, cured film, element and display device provided with cured film, and method for producing same 东丽株式会社 2021-10-08 CN disclosed