Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553237 | 0.84 | TDP1 (0.42) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL4621245 | 0.76 | TDP1 (0.58) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL27763136 | 0.74 | TDP1 (0.42) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL27658984 | 0.74 | TDP1 (0.42) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL6242838 | 0.73 | TDP1 (0.61) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL10804298 | 0.72 | TAAR1 (0.40) | ALDH1A1LMNATHRBKDM4EHIF1A | |
| SCHEMBL14228099 | 0.71 | TDP1 (0.52) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL2116681 | 0.71 | TDP1 (0.52) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL8466709 | 0.70 | TDP1 (0.47) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL8464853 | 0.69 | TDP1 (0.38) | TDP1ALDH1A1TSHRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463493-B | Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate | SIO2医药产品公司 | 2021-10-15 | — | — | CN | disclosed |