SCHEMBL4621245

SCHEMBL4621245

COC(C)Nc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.58
ALDH1A1 P00352 6/20 0.50
TSHR P16473 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 2/20 0.50
ALOX15 P16050 2/20 0.50
ALOX12 P18054 2/20 0.50
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
THRB P10828 1/20 0.50
RECQL P46063 1/20 0.50
ATM Q13315 1/20 0.50
GAA P10253 1/20 0.44
MAPK1 P28482 2/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 1/20 0.40
KCNH3 Q9ULD8 2/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7734438 0.87 ALDH1A1 (0.44) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL14228099 0.85 TDP1 (0.52) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL6242838 0.83 TDP1 (0.61) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL7734444 0.78 TDP1 (0.37) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL26087524 0.78 TDP1 (0.54) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL10864614 0.78 CA12 (0.46) TDP1ALDH1A1TSHRCYP3A4ALOX12
SCHEMBL448536 0.77 NR4A1 (0.45) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL8813184 0.77 TDP1 (0.54) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL28408433 0.77 TDP1 (0.54) TDP1ALDH1A1TSHRHSD17B10CYP3A4
SCHEMBL11526055 0.77 MAPT (0.50) ALDH1A1HSD17B10CYP3A4LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295474-B1 CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS L'OREAL (FR) 1991-07-17 EP claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
US-20250212684-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, COMPOUND, AND MANUFACTURING METHOD OF COMPOUND FUJIFILM CORPORATION (JP) 2025-06-26 US disclosed
WO-2023134608-A1 FUSED RING COMPOUNDS SERVING AS HPK1 INHIBITORS 微境生物医药科技(上海)有限公司 2023-07-20 WO disclosed
CN-112812061-B N-aryl-1, 2,3, 4-tetrahydroisoquinoline-7-amine compound and application thereof 苏州恩华生物医药科技有限公司 2022-04-22 CN disclosed
CN-113072819-A Disperse dye special for anhydrous dyeing system and preparation and application thereof 上海工程技术大学 2021-07-06 CN disclosed
CN-112812061-A N-aryl-1, 2,3, 4-tetrahydroisoquinoline-7-amine compound and application thereof 江苏恩华药业股份有限公司 2021-05-18 CN disclosed
US-9642847-B2 Combinational compositions and methods for treatment of cancer ARQULE, INC. (US) 2017-05-09 US disclosed
EP-1514873-B1 Process for oxidation of organic substrates and catalyst compositions for performing the same EVONIK DEGUSSA GMBH (DE) 2008-03-19 EP disclosed
US-20050075514-A1 Process for the oxidation of organic substrates and a catalyst composition for carrying out the process EVONIK DEGUSSA GMBH (DE) 2005-04-07 US disclosed
EP-1514873-A1 Process for oxidation of organic substrates and catalyst compositions for performing the same Degussa AG (DE) 2005-03-16 EP disclosed
EP-0124861-B1 LIGHT SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1989-01-25 EP disclosed
EP-0167173-B1 COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1987-12-23 EP disclosed
EP-0249453-A2 Silver halide color photographic light-sensitive material improved in cyan image characteristics KONICA CORPORATION (JP) 1987-12-16 EP disclosed
EP-0088563-B1 LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1987-09-23 EP disclosed
EP-0099234-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1987-04-29 EP disclosed
US-4101541-A DYES FOR POLYESTERS OR POLYPROPYLENE CIBA-GEIGY CORPORATION (US) 1978-07-18 US disclosed
US-4083847-A Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group CIBA-GEIGY CORPORATION (US) 1978-04-11 US disclosed
US-3987026-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1976-10-19 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250212684-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, COMPOUND, AND MANUFACTURING METHOD OF COMPOUND CRY1, CRY2, PRDM9 TDP1 3361/4885ALDH1A1 958/4885TSHR 4153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.