Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037549 | 0.93 | TSHR (0.44) | TSHRTHRBENPP2LPAR3LPAR1 | |
| SCHEMBL28874078 | 0.91 | TSHR (0.41) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL541550 | 0.90 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL20582579 | 0.90 | THRB (0.40) | TSHRTHRBENPP2LPAR3LPAR1 | |
| SCHEMBL28874076 | 0.88 | TSHR (0.41) | TSHRTHRBENPP2LPAR3LPAR1 | |
| SCHEMBL176509 | 0.84 | TSHR (0.40) | TSHRTHRBENPP2LPAR3LPAR1 | |
| SCHEMBL28874092 | 0.84 | TSHR (0.46) | TSHRTHRBENPP2LPAR3LPAR1 | |
| SCHEMBL2041337 | 0.84 | TSHR (0.39) | TSHRTHRB | |
| SCHEMBL541928 | 0.83 | TSHR (0.43) | TSHRTHRBSMN1; SMN2 | |
| SCHEMBL2040421 | 0.81 | TSHR (0.47) | TSHRTHRBLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463493-B | Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate | SIO2医药产品公司 | 2021-10-15 | — | — | CN | disclosed |