Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 3/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901695 | 1.00 | KDM4E (0.62) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL29535139 | 0.82 | KDM4E (0.66) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL7263029 | 0.82 | KDM4E (0.66) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL30864305 | 0.80 | TDP1 (0.67) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL5313776 | 0.79 | TYMS (0.72) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL3115005 | 0.79 | TYMS (0.72) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL31463101 | 0.79 | TYMS (0.72) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL6014177 | 0.79 | TYMS (0.72) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL29900526 | 0.79 | TYMS (0.72) | KDM4EHSD17B10LMNAPOLBNPSR1 | |
| SCHEMBL4755403 | 0.79 | TYMS (0.72) | PARP1TYMSGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-110590806-B | Chalcone analogue containing thieno [2,3-d ] pyrimidine-2-yl and preparation method and application thereof | 深圳大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-110590806-A | Chalcone analogue containing thieno [2,3-d ] pyrimidine-2-yl and preparation method and application thereof | 深圳大学 | 2019-12-20 | — | — | CN | disclosed |