Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 16/20 | 0.72 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647987 | 0.84 | TYMS (1.00) | TYMS | |
| SCHEMBL4311562 | 0.82 | TYMS (0.71) | TYMSQTRT1PARP1 | |
| SCHEMBL30249625 | 0.82 | TYMS (0.71) | TYMSQTRT1PARP1 | |
| SCHEMBL4753152 | 0.80 | QTRT1 (0.56) | TYMSQTRT1PARP1 | |
| SCHEMBL28637729 | 0.79 | KDM4E (0.62) | TYMSPARP1GUSB | |
| SCHEMBL10288872 | 0.79 | TYMS (0.72) | TYMSQTRT1PARP1 | |
| SCHEMBL29901695 | 0.79 | KDM4E (0.62) | TYMSPARP1GUSB | |
| SCHEMBL3672857 | 0.79 | TYMS (0.72) | TYMSQTRT1PARP1 | |
| SCHEMBL29850802 | 0.79 | TYMS (0.72) | TYMSQTRT1PARP1 | |
| SCHEMBL14084807 | 0.79 | QTRT1 (0.54) | TYMSQTRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |