Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478261 | 0.80 | HCRTR2 (0.33) | HCRTR2RECQL | |
| SCHEMBL28038229 | 0.80 | HCRTR2 (0.33) | HCRTR2 | |
| SCHEMBL28284532 | 0.80 | HCRTR2 (0.33) | HCRTR2RECQL | |
| SCHEMBL29286731 | 0.79 | HCRTR2 (0.32) | HCRTR2 | |
| SCHEMBL28145038 | 0.79 | USP2 (0.37) | HCRTR2RECQLUSP2SMN1; SMN2 | |
| SCHEMBL3057463 | 0.78 | — | — | |
| SCHEMBL28215932 | 0.78 | HCRTR2 (0.32) | HCRTR2 | |
| SCHEMBL28517071 | 0.78 | HCRTR2 (0.32) | HCRTR2 | |
| SCHEMBL28523544 | 0.77 | GRM2 (0.30) | — | |
| SCHEMBL27833576 | 0.77 | HCRTR2 (0.33) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675689-B | Chemical synthesis method of rosuvastatin intermediate | 浙江工业大学 | 2021-08-24 | — | — | CN | claimed |
| CN-113387944-B | Synthetic method of rosuvastatin calcium intermediate | 浙江宏元药业股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113387944-A | Synthetic method of rosuvastatin calcium intermediate | 浙江宏元药业股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-107778279-A | A kind of preparation method of Atorvastatin calcium intermediate | 江苏欧信制药有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-107602527-A | A kind of preparation method of statins drug midbody | 江苏欧信制药有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-106749927-A | A kind of preparation method of polycarbonate transparent product fire retardant | 衢州普信新材料有限公司 | 2017-05-31 | — | — | CN | disclosed |