SCHEMBL28478261

SCHEMBL28478261

CC(=O)OC(C)(C)C.CC1(C)OCC[C@@H](CO)O1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 1/20 0.33
RECQL P46063 1/20 0.31
CA2 P00918 1/20 0.31
NR1H2 P55055 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28284532 1.00 HCRTR2 (0.33) HCRTR2RECQLCA2NR1H2
SCHEMBL28038229 0.88 HCRTR2 (0.33) HCRTR2CA2
SCHEMBL29286731 0.87 HCRTR2 (0.32) HCRTR2CA2
SCHEMBL27833576 0.85 HCRTR2 (0.33) HCRTR2CA2
SCHEMBL30423996 0.82 CA2 (0.33) CA2
SCHEMBL29975910 0.82 CA2 (0.33) CA2
SCHEMBL3794449 0.82 CA2 (0.33) CA2
SCHEMBL13305484 0.82 CA2 (0.33) CA2
SCHEMBL1067073 0.81 MIF (0.34) HCRTR2RECQLCA2
SCHEMBL28638475 0.80 HCRTR2 (0.32) HCRTR2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111875538-B Synthetic method of pitavastatin tert-butyl ester 安徽省庆云医药股份有限公司 2022-05-17 CN disclosed
CN-109574998-B Synthetic method of pitavastatin calcium intermediate 安徽省庆云医药股份有限公司 2022-03-08 CN disclosed
CN-109574999-B Preparation method of pitavastatin calcium intermediate 安徽省庆云医药股份有限公司 2022-03-08 CN disclosed
CN-111875538-A Synthetic method of pitavastatin tert-butyl ester 安徽省庆云医药股份有限公司 2020-11-03 CN disclosed