SCHEMBL28638510

SCHEMBL28638510

CCOC(=O)c1ccc(N2C(=O)CSC2c2ccc(F)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 18/20 0.74
KMT2A Q03164 2/20 0.63
MEN1 O00255 1/20 0.63
GFER P55789 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19321978 0.85 HTR7 (1.00) HTR7
SCHEMBL19306306 0.85 HTR7 (1.00) HTR7
SCHEMBL19305976 0.84 HTR7 (1.00) HTR7
SCHEMBL19306204 0.82 HTR7 (1.00) HTR7KMT2AMEN1GFER
SCHEMBL19317365 0.81 HTR7 (0.61) HTR7KMT2AMEN1GFER
SCHEMBL28625981 0.80 HTR7 (0.59) HTR7
SCHEMBL19306073 0.80 HTR7 (0.89) HTR7
SCHEMBL19306362 0.79 HTR7 (0.87) HTR7
SCHEMBL19306007 0.79 HTR7 (1.00) HTR7
SCHEMBL28636466 0.79 HTR7 (0.66) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883099-B Thiazolidinone compounds and use thereof 石全 2021-09-28 CN disclosed