SCHEMBL2863860

SCHEMBL2863860

CC1C=C(C(C)(C)C)C=C1c1cccc2c1C(C(c1ccccc1)c1ccccc1)c1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2873614 0.93
SCHEMBL2860626 0.91
SCHEMBL8211118 0.89
SCHEMBL2870244 0.83 NPC1 (0.32)
SCHEMBL5089538 0.79
Hydrochloric Acid SCHEMBL2804316 0.78
SCHEMBL2868966 0.76 MEN1 (0.33) MEN1POLBKMT2AATM
Hydrochloric Acid SCHEMBL12815046 0.69 MEN1 (0.41) MEN1POLBKMT2AATM
Hydrochloric Acid SCHEMBL4323455 0.68 ALDH1A1 (0.40) MEN1KMT2A
SCHEMBL3157929 0.67 MEN1 (0.52) MEN1POLBKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-20090043050-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2009-02-12 US disclosed