Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | DDT | P30046 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861379 | 0.93 | MAPK13 (0.48) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2854567 | 0.88 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2859964 | 0.86 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2858895 | 0.86 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2852365 | 0.85 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2850785 | 0.85 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2850877 | 0.84 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2857950 | 0.84 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2856640 | 0.84 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14NPC1 | |
| SCHEMBL2856833 | 0.83 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828148-B1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-01-20 | — | — | EP | claimed |