Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 6/20 | 0.75 |
| ▸ | MAOA | P21397 | 1/20 | 0.75 |
| ▸ | CASP3 | P42574 | 12/20 | 0.49 |
| ▸ | CASP7 | P55210 | 11/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 2/20 | 0.43 |
| ▸ | CASP9 | P55211 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259720 | 0.86 | LOX (0.77) | LOXMAOACASP3CASP7LOXL2 | |
| SCHEMBL19259710 | 0.86 | LOX (0.77) | LOXMAOACASP3CASP7LOXL2 | |
| SCHEMBL19259756 | 0.85 | LOX (1.00) | LOXMAOACASP3CASP7LOXL2 | |
| SCHEMBL19259758 | 0.85 | LOX (1.00) | LOXMAOACASP3CASP7LOXL2 | |
| SCHEMBL28644275 | 0.83 | LOX (0.74) | LOXMAOACASP3CASP7LOXL2 | |
| Hydrochloric Acid SCHEMBL28656808 | 0.75 | LOXL2 (0.70) | LOXMAOALOXL2 | |
| SCHEMBL19274289 | 0.73 | LOX (0.79) | LOXMAOALOXL2 | |
| SCHEMBL19274288 | 0.73 | LOX (1.00) | LOXMAOALOXL2 | |
| SCHEMBL19259965 | 0.72 | LOX (0.57) | LOXMAOACASP3CASP7CASP2 | |
| SCHEMBL19259964 | 0.72 | LOX (0.57) | LOXMAOACASP3CASP7CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |