SCHEMBL2863889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862915	0.86	TTK (0.68)	TTKLRRK2PDPK1HDAC1AURKA
	SCHEMBL2570957	0.78	TTK (1.00)	TTK
	SCHEMBL4379912	0.76	TTK (0.56)	TTKTHRBPDPK1HDAC1AURKA
	SCHEMBL12281457	0.73	TTK (0.90)	TTK
	SCHEMBL12282790	0.73	TTK (0.88)	TTK
	SCHEMBL2567732	0.72	TTK (0.76)	TTKAURKA
	SCHEMBL8260089	0.72	TTK (0.69)	TTKLRRK2ITKAURKAJAK2
	SCHEMBL12741328	0.72	CFTR (0.57)	TTKTHRBHDAC1NR2E3LMNA
	Trifluoroacetic Acid SCHEMBL2572640	0.72	TTK (0.81)	TTKAURKA
	SCHEMBL8251866	0.71	JAK2 (0.74)	LRRK2PDPK1ITKAURKAJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.